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FIGURE 3 In order to evaluate endosomal escape over time, PEG-coated NPs were co-loaded with a mixture of EGFP mRNA and Cy3-labeled siRNA, and subsequently incubated with C28/I2 cells for 3, 24 and 48 h

SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells

Urinary leukotriene E(4) and prostaglandin D(2) metabolites increase in adult and childhood severe asthma characterized by type 2 inflammation

(2025) Although there is extensive evidence that mechanisms of APAP hepatotoxicity translate to human overdose patients, the vast majority of experiments are performed in young and healthy male mice, which does not reflect the entire spectrum of patients in terms of age, sex, pre-existing conditions, consumption of multiple drugs, etc